Best Overall Response-associated Signature to Doxorubicin in Soft Tissue Sarcomas: A Transcriptomic Analysis from ANNOUNCE

CONCLUSIONS: The refined REDSARC signature provides a potential tool to direct the application of doxorubicin in sarcomas and other malignancies. Validation and further refinement of the signature in other potentially subtype specific prospective cohorts is recommended.PMID:38536068 | DOI:10.1158/1078-0432.CCR-23-3936

Source: Clinical Cancer Research - March 27, 2024 Category: Cancer & Oncology Authors: Jiangang Liu David S Moura Robin L Jones Amit Aggarwal Ebert J Philip Andrew J Wagner Jennifer Wright Javier Mart ín-Broto William D Tap Source Type: research