A brainstem–hypothalamus neuronal circuit reduces feeding upon heat exposure

Nature, Published online: 27 March 2024; doi:10.1038/s41586-024-07232-3In response to acute thermal challenge, thermosensing glutamatergic neurons of the parabrachial nucleus in mouse brain activate tanycytes, which reduce the excitability of Flt1-expressing dopamine and agouti-related peptide-containing neurons, thus suppressing appetite.

Source: Nature AOP - March 27, 2024 Category: Research Authors: Marco Benevento Al án Alpár Anna Gundacker Leila Afjehi Kira Balueva Zsofia Hevesi J ános Hanics Sabah Rehman Daniela D. Pollak Gert Lubec Peer Wulff Vincent Prevot Tamas L. Horvath Tibor Harkany Source Type: research