Low-frequency and rare genetic variants associated with rheumatoid arthritis risk

Nature Reviews Rheumatology, Published online: 27 March 2024; doi:10.1038/s41584-024-01096-7Rheumatoid arthritis has a substantial genetic component, some of which is associated with the presence of low-frequency or rare variants. Next-generation sequencing in large and well-defined cohorts can continue to identify these variants and thereby contribute to the future prediction, diagnosis and treatment of rheumatoid arthritis.
Source: Nature Reviews Rheumatology - Category: Rheumatology Authors: Source Type: research