Osteopontin promotes tumor growth and metastasis and GPX4-mediated anti-lipid peroxidation in triple-negative breast cancer by activating the PI3k/Akt/mTOR pathway

CONCLUSION: OPN promoted tumor sphere formation and angiogenesis in TNBC by activating the PI3K/AKT/mTOR pathway to regulate GPX4-mediated anti-lipid peroxidation levels.PMID:38526702 | DOI:10.1007/s00432-024-05658-w
Source: Clinical Genitourinary Cancer - Category: Cancer & Oncology Authors: Source Type: research