The Impact of Initial Tumor Response on Survival Outcomes of Patients With HER2-Positive Advanced Breast Cancer Treated With Docetaxel, Trastuzumab, and Pertuzumab: An Exploratory Analysis of the CLEOPATRA Trial

CONCLUSIONS: Our findings suggest that radiological CR at first disease re-evaluation is associated with more prolonged survival; this might result from stronger dependence on HER2 pathway addiction, supporting the need for further translational research.PMID:38514306 | DOI:10.1016/j.clbc.2024.02.012

Source: Clinical Genitourinary Cancer - March 21, 2024 Category: Cancer & Oncology Authors: Veronique Debien Elisa Agostinetto Marco Bruzzone Marcello Ceppi Diogo Martins-Branco Chiara Molinelli Flavia Jacobs Guilherme Nader-Marta Matteo Lambertini Evandro de Azambuja Source Type: research