miRNA ‑21 promotes the progression of acute liver failure via the KLF6/autophagy/IL‑23 signaling pathway

In conclusion, in the present study, baseline serum miR‑21 levels were highly upregulated in patients with ALF, antagomir‑21 attenuated LPS/GalN‑induced ALF in a mouse model, and miR‑21 could promote the expression of IL‑23 via inhibiting KLF6.PMID:38516774 | DOI:10.3892/mmr.2024.13205
Source: Molecular Medicine Reports - Category: Molecular Biology Authors: Source Type: research