Comparison of Clinicopathological Features of Pleomorphic and Invasive Lobular Breast Carcinomas

CONCLUSION: We discovered that pleomorphic type was associated with higher grades, estrogen receptor negativity, and Ki-67 expression. The incidence of metachronous breast cancer was high in the pleomorphic group, which may be a noteworthy finding to be considered in follow-ups. In addition, the high rates of multicentricity and multifocality of tumors in the pleomorphic group may be associated with increased surgical margin positivity and a higher likelihood of mastectomy. In a nutshell, our findings may guide patients and surgeons regarding the type of intervention and reconstruction options to be adopted in prospective surgeries.PMID:38513191 | DOI:10.1177/00031348241241612

Source: The American Surgeon - March 21, 2024 Category: Surgery Authors: Mehmet F Sa ğdıç Onur C G üler Orkun Suba şı Özhan Albayrak Cihangir Özaslan Source Type: research