Indole-3-carboxyaldehyde does not reverse the intestinal effects of fiber-free diet in mice

ConclusionsFiber-free diet lowered colonic content of I3A in mice. I3A stimulates GLP-1 secretion in vitro, but not in animal studies. Moreover, it has no evident beneficial effect on intestinal health when administered in vivo.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research