Critical appraisal of surgical margins according to KRAS status in liver resection for colorectal liver metastases: Should surgical strategy be influenced by tumor biology?

KRAS mutation is a negative prognostic factor for colorectal liver metastases. Several studies have investigated the resection margins according to KRAS status, with conflicting results. The aim of the study was to assess the oncologic outcomes of R0 and R1 resections for colorectal liver metastases according to KRAS status.

https://www.surgjournal.com/article/S0039-6060(24)00071-0/fulltext?rss=yes

Source: Surgery - March 21, 2024 Category: Surgery Authors: Rami Rhaiem, Adrien Duram é, Florian Primavesi, Dimitri Dorcaratto, Nicholas Syn, Ángela de la Hoz Rodríguez, Aurélien Dupré, Tullio Piardi, Gerardo Blanco Fernández, Arancha Prada Villaverde, Juan C. Rodríguez Sanjuán, Roberto Fernández Santiago Source Type: research