Targeting STAT6-mediated synovial macrophage activation improves pain in experimental knee osteoarthritis

Pain from osteoarthritis (OA) is one of the top causes of disability worldwide, but effective treatment is lacking. Nociceptive factors are released by activated synovial macrophages in OA, but depletion of sy...

Source: Arthritis Research and Therapy - March 20, 2024 Category: Rheumatology Authors: Garth Blackler, Yue Lai-Zhao, Joseph Klapak, Holly T. Philpott, Kyle K. Pitchers, Andrew R. Maher, Benoit Fiset, Logan A. Walsh, Elizabeth R. Gillies and C. Thomas Appleton Tags: Research Source Type: research