Quantification of ventricular stress in univentricular hearts during early childhood using age-independent zlog-NT-proBNP
Children with univentricular hearts (UVH) undergo up to three palliative surgical procedures to achieve complete circulatory separation (Fontan circulation). As a marker of cardiac wall stress, NT-proBNP is a promising tool to assess systemic ventricular load in these patients. However, different reference intervals (RI) apply to each stage, as NT-proBNP is highly age-dependent.
Source: International Journal of Cardiology - Category: Cardiology Authors: Jonas Palm, Masamichi Ono, Carolin Niedermaier, J ürgen Hörer, Georg Hoffmann, Stefan Holdenrieder, Frank Klawonn, Peter Ewert Source Type: research