Combined polygenic scores for ischemic stroke risk factors aid risk assessment of ischemic stroke

Current risk assessment for ischemic stroke (IS) is limited to clinical variables. We hypothesize that polygenic scores (PGS) of IS (PGSIS) and IS-associated diseases such as atrial fibrillation (AF), venous thromboembolism (VTE), coronary artery disease (CAD), hypertension (HTN), and Type 2 diabetes (T2D) may improve the performance of IS risk assessment.

Source: International Journal of Cardiology - March 21, 2024 Category: Cardiology Authors: Sarah Huang, Abhishek Joshi, Zhuqing Shi, Jun Wei, Huy Tran, S. Lilly Zheng, David Duggan, Annabelle Ashworth, Liana Billings, Brian T. Helfand, Arman Qamar, Zachary Bulwa, Alfonso Tafur, Jianfeng Xu Source Type: research