MiR-135a-5p regulates window of implantation by suppressing pinopodes development and decidualization of endometrial stromal cells

ConclusionMiR-135a-5p expression is significantly downregulated during the WOI. High miR-135a-5p levels suppress pinopode development and endometrial tissue decidualization through HOXA10 and BMPR2, contributing to inadequate endometrial receptivity.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research