Deep-learning automated quantification of longitudinal OCT scans demonstrates reduced RPE loss rate, preservation of intact macular area and predictive value of isolated photoreceptor degeneration in geographic atrophy patients receiving C3 inhibition treatment

Conclusion
The OCT evidence suggests that pegcetacoplan slows progression of cRORA overall and RPE loss specifically while protecting the remaining photoreceptors and slowing the progression of healthy retina to iRORA.

Source: British Journal of Ophthalmology - March 20, 2024 Category: Opthalmology Authors: Fu, D. J., Glinton, S., Lipkova, V., Faes, L., Liefers, B., Zhang, G., Pontikos, N., McKeown, A., Scheibler, L., Patel, P. J., Keane, P. A., Balaskas, K. Tags: Open access, Editor's choice Retina Source Type: research