Enhancer of zeste homolog 2 facilitates phenotypic transition of vascular smooth muscle cells leading to aortic aneurysm/dissection

In conclusion, the present study identified a previously unrecognized EZH2-ITGB3 regulatory axis and thus provides novel mechanistic insights into the pathophysiological function of EZH2. EZH2 may thus serve as a potential target for the management of TAAs.PMID:38476905 | PMC:PMC10928840 | DOI:10.3892/etm.2024.12433
Source: Experimental and Therapeutic Medicine - Category: General Medicine Authors: Source Type: research