Exploring the Link Between Thyrotoxicosis and Cognitive Decline in Older Adults

To the Editor In the pivotal cohort study by Adams et al, an in-depth evaluation of the association between thyrotoxicosis and cognitive decline in older individuals was conducted. Analyzing data from 65  931 individuals 65 years and older within the Johns Hopkins Community Physicians Network (2014-2023), the study discerns a critical association between reduced thyrotropin levels and elevated occurrences of cognitive impairments, including dementia. Notably, the study identified a 1.39-fold incre ase in cognitive disorder risk in patients with thyrotoxicosis, spotlighting the need for measured thyroid hormone prescription practices amid concerns of widespread use and potential overtreatment.
Source: JAMA Internal Medicine - Category: Internal Medicine Source Type: research