Metabolic etiologies in children with infantile epileptic spasm syndrome: Experience at a tertiary pediatric neurology center

Infantile epileptic spasm syndrome (IESS) includes both West syndrome (WS) and infants exhibiting epileptic spasms without meeting all WS criteria [1]. WS is characterized by infantile spasms (IS), hypsarrhythmia (an interictal electroencephalography (EEG) pattern with irregular, high-amplitude slow waves on a chaotic background), and neurodevelopmental delay (1). Manifesting in early infancy, WS often has a poor prognosis [2 –4]. The incidence of WS has been estimated to be 0.24 %-0.42 %, with a higher incidence in males [5,6].
Source: Brain and Development - Category: Neurology Authors: Tags: Original Article Source Type: research