Conversion of Olmesartan to Olmesartan Medoxomil, A Prodrug that Improves Intestinal Absorption, Confers Substrate Recognition by OATP2B1

ConclusionOlmesartan-MX is a substrate for OATP2B1, and the naringin-sensitive transport system contributes to the improved intestinal absorption of olmesartan-MX compared with its parent drug, olmesartan.

http://link.springer.com/10.1007/s11095-024-03687-1

Source: Pharmaceutical Research - March 14, 2024 Category: Drugs & Pharmacology Source Type: research