Conversion of Olmesartan to Olmesartan Medoxomil, A Prodrug that Improves Intestinal Absorption, Confers Substrate Recognition by OATP2B1

CONCLUSION: Olmesartan-MX is a substrate for OATP2B1, and the naringin-sensitive transport system contributes to the improved intestinal absorption of olmesartan-MX compared with its parent drug, olmesartan.PMID:38485855 | DOI:10.1007/s11095-024-03687-1

Source: Cell Research - March 15, 2024 Category: Cytology Authors: Naomi Fukazawa Tomohiro Nishimura Keisuke Orii Saki Noguchi Masatoshi Tomi Source Type: research