Pretreatment with a dual antiplatelet and anticoagulant (APAC) reduces ischemia –reperfusion injury in a mouse model of temporary middle cerebral artery occlusion—implications for neurovascular procedures

ConclusionsPretreatment with APAC or UFH was safe and effective in reducing brain injury in a model of cerebral ischemia induced by transient middle cerebral artery occlusion. Further studies on the use of APAC to limit ischemic injury during temporary occlusion in neurovascular procedures are indicated.
Source: Acta Neurochirurgica - Category: Neurosurgery Source Type: research