Brain MRI in status epilepticus: Relevance of findings

Rev Neurol (Paris). 2024 Mar 11:S0035-3787(24)00423-5. doi: 10.1016/j.neurol.2023.12.011. Online ahead of print.ABSTRACTStatus epilepticus (SE) represents one of the most common neurological emergencies, associated with high mortality and an important risk of functional sequelae in survivors. Magnetic resonance imaging (MRI) offers the possibility of early and noninvasive observation of seizure-induced parenchymal disturbances secondary to the epileptic process. In the present review, we propose a descriptive and comprehensive understanding of current knowledge concerning seizure-induced MRI abnormalities in SE, also called peri-ictal MRI abnormalities (PMAs). We then discuss how PMAs, as a noninvasive biomarker, could be helpful to optimize patient prognostication in SE management. Finally, we discuss alternative promising MRI approaches, including arterial spin labeling (ASL), susceptibility-weighted imaging (SWI), dynamic contrast-enhanced (DCE) MRI and dynamic susceptibility contrast (DSC) MRI that could refine our understanding of SE, particularly in non-convulsive form.PMID:38472033 | DOI:10.1016/j.neurol.2023.12.011

Source: Revue Neurologique - March 12, 2024 Category: Neurology Authors: T Bonduelle M Ollivier A Gradel J Aupy Source Type: research