The Future of Neonatal Cerebral Oxygenation Monitoring: Directions after the SafeBoosC-III Trial

Perinatal and neonatal perturbations in cerebral hemodynamics and oxygenation are significant risk factors for brain injury and subsequent neurodevelopmental impairment in preterm infants.1,2 The use of near-infrared spectroscopy (NIRS) to non-invasively monitor cerebral oxygen saturation (rScO2) and minimize cerebral hypoxia is a promising strategy to reduce brain injury in the extremely and very preterm infant.3 Although increasingly used as a clinical tool to monitor cerebral oxygenation and perfusion of the individual infant, randomized controlled trials evaluating the benefit of an interventional strategy to reduce cerebral hypoxia using NIRS-derived rScO2 monitoring have been largely lacking.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Commentary Source Type: research