Early Treatment With Mesenchymal Stromal Cells Prevents Development of Long-term Radiation Induced Salivary Dysfunction

There is a critical need for a treatment that will safely and effectively prevent the development of radiation-induced xerostomia (RIX) or salivary dysfunction. We preformed preclinical studies to test the ability of IFN- ɣ stimulated marrow-derived mesenchymal stromal cells (MSC(M)) to prevent the development of long-term salivary dysfunction in a mouse model.

https://www.redjournal.org/article/S0360-3016(24)00162-7/fulltext?rss=yes

Source: International Journal of Radiation Oncology * Biology * Physics - March 14, 2024 Category: Radiology Authors: C. Paz, A.G. Frick, K.P. Nickel, I. Gurevic, G.C. Blitzer, S.S. McCoy, R.J. Kimple Tags: 183 Source Type: research