SAP-expressing T peripheral helper cells identify systemic lupus erythematosus patients with lupus nephritis

ConclusionThe expansion of SAP-expressing T helper cells was associated with LN in our cohort and verified using scRNA-seq data of renal infiltrating T cells. Improved SLAM and SAP signaling understanding can identify new therapeutic targets in LN.
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research