Lower body mass and lower adiposity are associated with differential responses to two treatment strategies for rheumatoid arthritis

Conclusions
Lower BMI and evidence of lower adiposity based on adipokine profiles were associated with a superior response to TNFi compared with triple therapy. There was no difference between treatments among overweight/obese participants. The results support TNFi being a particularly important therapeutic among normal/underweight patients, with implications for clinical decisions and trial design.

Source: Annals of the Rheumatic Diseases - March 12, 2024 Category: Rheumatology Authors: Baker, J. F., ODell, J. R., England, B. R., Giles, J. T., Newcomb, J. A., George, M. D., Thiele, G., Moreland, L., Bridges, S. L., Curtis, J. R., Mikuls, T. R. Tags: ARD, Rheumatoid arthritis Source Type: research