High TPX2 expression results in poor prognosis, and Sp1 mediates the coupling of the CX3CR1/CXCL10 chemokine pathway to the PI3K/Akt pathway through targeted inhibition of TPX2 in endometrial cancer

ConclusionTPX2 could be a prognostic biomarker for EC and play an important role in the CX3CR1/CXCL10 chemokine pathway and PI3K/Akt pathway via Sp1.

Source: Cancer Medicine - March 11, 2024 Category: Cancer & Oncology Authors: Mei Yang, Xiaogang Mao, Lin Li, Jiang Yang, Hui Xing, Chunfan Jiang Tags: RESEARCH ARTICLE Source Type: research