Recrudescence of Severe Carbamazepine- Induced DRESS Syndrome after Initiation of Levetiracetam

We report a patient with severe DRESS syndrome precipitated by aromatic AED carbamazepine with recrudescence approximately 2 weeks after substitution with nonaromatic AED levetiracetam. The patient was treated with high-dose corticosteroids and switched to the benzodiazepine AED clobazam. At follow-up appointment several weeks later, the patient's rash, liver injury, and eosinophilia had resolved.PMID:38051248

Source: Skinmed - December 5, 2023 Category: Dermatology Authors: Simon W Jiang Lauren Floyd Adela R Cardones M Angelica Selim Sabrina M Shearer Source Type: research