Gastric cancer secreted miR-214-3p inhibits the anti-angiogenesis effect of apatinib by suppressing ferroptosis in vascular endothelial cells

In conclusion, inhibition of miR-214-3p can increase the sensitivity of vascular endothelial cells to Apatinib, thereby promoting the antiangiogenic effect of Apatinib, suggesting a potential combination therapy for advanced gastric cancer.PMID:38370339 | PMC:PMC10874472 | DOI:10.32604/or.2023.046676

Source: Oncology Research - February 19, 2024 Category: Cancer & Oncology Authors: Weixue Wang Tongtong Wang Yan Zhang Ting Deng Haiyang Zhang Y I Ba Source Type: research