Evidence for Locus Coeruleus –Norepinephrine System Abnormality in Military Posttraumatic Stress Disorder Revealed by Neuromelanin-Sensitive Magnetic Resonance Imaging

The complex neurobiology of posttraumatic stress disorder (PTSD) calls for the characterization of specific disruptions in brain functions that require targeted treatment. One such alteration could be an overactive locus coeruleus (LC) –norepinephrine system, which may be linked to hyperarousal symptoms, a characteristic and burdensome aspect of the disorder.

Source: Biological Psychiatry - January 28, 2024 Category: Psychiatry Authors: Adelina McCall, Reihaneh Forouhandehpour, Seyda Celebi, Claude Richard-Malenfant, Rami Hamati, Synthia Guimond, Lauri Tuominen, David Weinshenker, Natalia Jaworska, Robyn J. McQuaid, Jakov Shlik, Rebecca Robillard, Zachary Kaminsky, Clifford M. Cassidy Tags: Archival Report Source Type: research