Comprehensive Domain-Specific Analysis and IgG Profiling of anti-FVIII Antibodies using a bead-based multiplex immunoassay

CONCLUSION: LumiTope assay provides a sensitive and specific method for detection but also domain specification of anti-FVIII-antibodies. Implementation of bead-based assays could improve antibody detection, profiling, comparability of results, and can complement NBA.PMID:38453023 | DOI:10.1016/j.jtha.2024.02.016

Source: Thrombosis and Haemostasis - March 7, 2024 Category: Hematology Authors: Behnaz Pezeshkpoor Ann-Cristin Berkemeier Kerstin Herbst Thilo Albert Jens M üller Johannes Oldenburg Source Type: research