Well-differentiated liposarcomas and dedifferentiated liposarcomas: Systemic treatment options for two sibling neoplasms

Soft tissue sarcomas are a heterogeneous group of neoplasms with both simple and complex karyotypes, representing 0.7  % of all cancers [1]. Adipocytic neoplasms are among the most common mesenchymal tumors, with liposarcomas accounting for approximately 20 % of all soft tissue sarcomas [2]. Liposarcoma presents primarily as tumors in adults, with a peak incidence between the ages of 50 to 65; however, a small proportion of liposarcoma cases are seen in younger populations [3]. Liposarcoma can be divided into three main categories: (1) atypical lipomatous tumors or well-differentiated liposarcoma (ALT or WDLPS) and dedifferentiated liposarcoma (DDLPS), (2) myxoid-round cell sarcoma, and (3) pleomorphic sa rcoma.
Source: Cancer Treatment Reviews - Category: Cancer & Oncology Authors: Tags: Systematic or Meta-analysis Studies Source Type: research