Human Neutrophils Couple Nitric Oxide Production and Extracellular Traps Formation in Allergic Asthma

CONCLUSIONS: Our findings reveal a novel role of neutrophils as the unique allergen/IgE-dependent NO source in allergic asthma enhancing ETs formation. These results suggest that NO produced by neutrophils needs further consideration in the treatment of allergic asthma.PMID:38445953 | DOI:10.1164/rccm.202305-0889OC

Source: Am J Respir Crit Car... - March 6, 2024 Category: Intensive Care Authors: Pedro Chac ón Antonio Vega-Rioja Bouchra Doukkali Alberto Del Valle Rodriguez Lourdes Fern ández-Delgado Leticia Dom ínguez-Cereijo Carmen Segura Beatriz Mar ía Pérez-Machuca James R Perkins Rajaa El Bekay Jos é Antonio Cornejo-García Nabil Hajji J Source Type: research