Hype or hope? High placebo response in major depression treatment with ketamine and esketamine: a systematic review and meta-analysis

ConclusionKetamine and esketamine show large antidepressant effects. However, our findings suggest that the placebo response plays a significant role in the antidepressant response and should be used for the benefit of the patients in clinical practice.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42022377591.
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research