Discovery of circulating blood biomarkers in patients with and without Modic changes of the lumbar spine: a preliminary analysis

ConclusionThis “proof-of-concept” study is the first to identify specific and significantly circulating blood biomarkers associated with symptomatic patients with lumbar MC, independent of disc alterations of degeneration and/or bulges/herniations. Specifically, differences in CCL5 and MIF protein levels were significantly noted in MC patients compared to those without MC.
Source: European Spine Journal - Category: Orthopaedics Source Type: research