DNA Methylation-Based Diagnosis and Treatment of Breast Cancer

This article focuses on the relevance of DNA methylation to breast cancer, describing the role of detecting DNA methylation in the early diagnosis, prediction, progression, metastasis, treatment, and prognosis of breast cancer, as well as recent advances. The reversibility of DNA methylation is utilized to target specific methylation aberrant promoters as well as related enzymes, from early prevention to late targeted therapy, to understand the journey of DNA methylation in breast cancer with a more comprehensive perspective. Meanwhile, methylation inhibitors in combination with other therapies have a wide range of prospects, providing hope to drug-resistant breast cancer patients.PMID:38441008 | DOI:10.2174/0115680096278978240204162353
Source: Current Cancer Drug Targets - Category: Cancer & Oncology Authors: Source Type: research