Physiologically Based Pharmacokinetic Modeling to Unravel the Drug-gene Interactions of Venlafaxine: Based on Activity Score-dependent Metabolism by CYP2D6 and CYP2C19 Polymorphisms

ConclusionsIn clinical practice, the impact of genotyping on thein vivo disposition process of VEN should be considered to ensure the safety and efficacy of treatment.
Source: Pharmaceutical Research - Category: Drugs & Pharmacology Source Type: research