Reassuring pregnancy outcomes in women with mild COL4A3-5 –related disease (Alport Syndrome) and genetic type of disease can aid personalized counseling

Individualized pre-pregnancy counseling and antenatal care for women with chronic kidney disease (CKD) require disease-specific data. Here, we investigated pregnancy outcomes and long-term kidney function in women with COL4A3-5 related disease (Alport Syndrome, (AS)) in a large multicenter cohort. The ALPART-network (mAternaL and fetal PregnAncy outcomes of women with AlpoRT syndrome), an international collaboration of 17 centers, retrospectively investigated COL4A3-5 related disease pregnancies after the 20th week.

Source: Kidney International - February 18, 2024 Category: Urology & Nephrology Authors: Margriet E. Gosselink, Rozemarijn Snoek, Agne Cerkauskaite-Kerpauskiene, Sophie P.J. van Bakel, Renee Vollenberg, Henk Groen, Rimante Cerkauskiene, Marius Miglinas, Rossella Attini, K álmán Tory, Kathleen Claes, Kristel van Calsteren, Aude Servais, Marg Tags: clinical investigation Source Type: research