The causal association between circulating cytokines with the risk of frailty and sarcopenia under the perspective of geroscience

ConclusionGenetic predisposition to assess IL-10, IL-12, and VEGF levels was associated with a higher risk of low hand grip strength and M-CSF with the presence of appendicular lean mass. The high levels of TNF-β and MIG were associated with a higher risk of frailty. More studies will be required to explore the molecular biological mechanisms underlying the action of inflammatory factors.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research