Excoriation disorder is characterized by systemic glutamatergic dysfunction

Excoriation disorder (ED), also known as neurotic excoriations, is a psychocutaneous disorder characterized by repetitive, compulsive picking of the skin leading to secondary tissue damage (Brown et al., 2015, Grant et al., 2012, Roh et al., 2022). ED carries an estimated prevalence of 1.4% (Keuthen et al., 2010), and is associated with significant social dysfunction, as patients often spend several hours each day performing compulsive behaviors leading to absence from work, school, or other social events (Grant et al., 2012).

Source: Journal of Investigative Dermatology - March 4, 2024 Category: Dermatology Authors: Zachary A. Bordeaux, Sriya V. Reddy, Emily Z. Ma, Hannah Cornman, Thomas Pritchard, Melika Marani, Weiying Lu, Shenghao Guo, Cissy Zhang, Pratik Khare, Anne Le, Madan M. Kwatra, Shawn G. Kwatra Tags: Letters to the Editor Source Type: research