AMPK α2 promotes tumor immune escape by inducing CD8+ T-cell exhaustion and CD4+ Treg cell formation in liver hepatocellular carcinoma

Adenosine monophosphate-activated protein kinase (AMPK) is associated with the development of liver hepatocellular carcinoma (LIHC). AMPK α2, an α2 subunit of AMPK, is encoded by PRKAA2, and functions as the catal...

Source: BMC Cancer - March 1, 2024 Category: Cancer & Oncology Authors: Yan Ouyang, Yan Gu, Xinhai Zhang, Ya Huang, Xianpeng Wei, Fuzhou Tang and Shichao Zhang Tags: Research Source Type: research