Radical prostatectomy cancer grade and percentage of Gleason pattern 4 estimated by global vs individual tumor grading correlate differently with the risk of biochemical recurrence in Grade Group 2 and 3 cancers

CONCLUSIONS: Grade Group, GP4%, and margin status derived by global vs individual tumor grading predict postoperative biochemical recurrence statistically significantly differently. This difference has important implications if results derived from cohorts graded using different methods are compared.PMID:38412318 | DOI:10.1093/ajcp/aqae003

Source: American Journal of Clinical Pathology - February 27, 2024 Category: Pathology Authors: Oleksandr N Kryvenko Jonathan I Epstein Ali Merhe Oleksii A Iakymenko Ricardo De Almeida E Silva Dimple Kumar Chanamolu Laurence M Briski Deukwoo Kwon Ivan Nemov Sanoj Punnen Alan Pollack Radka Stoyanova Dipen J Parekh Merce Jorda Mark L Gonzalgo Source Type: research