GSE234046 Single-cell RNA-sequencing of stromal vascular cells (SVCs) from the epididymal fat of obese mice.

Contributors : Theresa V Rohm ; Jerrold M OlefskySeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe obesity epidemic continues to worsen worldwide, driving metabolic and chronic inflammatory diseases. Thiazolidinediones (TZDs), such as rosiglitazone (Rosi), are PPARy ligands that promote anti-inflammatory changes in adipose tissue macrophages (ATMs) and cause insulin sensitization. We performed single-cell RNA-seuqnecing (scRNA-seq) to analyze the diversity and the phenotype of ATM subpopulations under Rosi and ATM-Exosome treatment.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research