OGT-induced O-GlcNAcylation of NEK7 protein aggravates osteoarthritis progression by enhancing NEK7/NLRP3 axis

CONCLUSION: OGT-induced NEK7 O-GlcNAcylation promotes OA progression by promoting chondrocyte pyroptosis via the suppressing interaction between NEK7 and NLRP3.PMID:38389178 | DOI:10.1080/08916934.2024.2319202

Source: Autoimmunity - February 23, 2024 Category: Allergy & Immunology Authors: Chunlei He Qiang Wu Zhaogan Zeng Yadong Yang Huabin He Meiyu Hu Sheng Liu Source Type: research