A potential link between inflammatory profiles, clinical pain, pain catastrophizing and long ‐term outcomes after total knee arthroplasty surgery

ConclusionsThe present exploratory study suggests that low-grade inflammation might be present in a subset of patients with high pain, high catastrophizing and low function 5  years after TKR. These exploratory results provide insights into some of the long-term postoperative complications after TKR surgery.Significance StatementThis exploratory study evaluated a subset of inflammatory markers and the association to clinical pain intensity, knee function and pain catastrophizing in patients 5  years after total knee replacement surgery. Our results provide insights into the understanding of the underlying mechanisms that may drive the long experience of pain after TKR surgery.

Source: European Journal of Pain - February 27, 2024 Category: Anesthesiology Authors: Rocco Giordano, Camilla Capriotti, Maria Carla Gerra, Andreas Kappel, Svend Erik Østgaard, Cristina Dallabona, Lars Arendt‐Nielsen, Kristian Kjær‐Staal Petersen Tags: ORIGINAL ARTICLE Source Type: research