Functional effects of an African glucose-6-phosphate dehydrogenase (G6PD) polymorphism (Val68Met) on red blood cell hemolytic propensity and post-transfusion recovery

DISCUSSION: This novel mouse model of the common G6PD A- variant has impaired antioxidant capacity like humans and low G6PD activity may reduce survival of transfused RBCs when irradiation is performed.PMID:38400625 | DOI:10.1111/trf.17756

Source: Transfusion - February 24, 2024 Category: Hematology Authors: Ling Wang Elizabeth R Rochon Sebastien Gingras Benjamin E Zuchelkowski Derek J Sinchar Elimira Alipour Julie A Reisz Minying Yang Grier P Page Tamir Kanias Darrell J Triulzi Janet S Lee Daniel B Kim-Shapiro Angelo D'Alessandro Mark T Gladwin Source Type: research