Structural optimization and biological evaluation of ML364 based derivatives as USP2a inhibitors

In conclusion, compound 8v has been identified as a potent USP2a inhibitor with substantial potential for cancer therapy.PMID:38401359 | DOI:10.1016/j.bioorg.2024.107222

Source: Bioorganic Chemistry - February 24, 2024 Category: Chemistry Authors: Youngchai Son Ji Su Yang Sang Chul Shin Seo Kyoung Park Yeojin Kim Jinyoung Park Jinha Yu Source Type: research