Targeting glutamine metabolism exhibits anti-tumor effects in thyroid cancer

ConclusionsThyroid cancer exhibited enhanced glutamine metabolism, as evidenced by the glutamine dependence of thyroid cancer cells and high expression of multiple glutamine metabolism-related genes. Targeting glutamine metabolism with DON prodrug could be a promising therapeutic option for advanced thyroid cancer.
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research