Seizure control and complications in patients switching from clobazam to clonazepam due to drug shortage

CONCLUSION: The abrupt switch from CLB to CLZ was observed to increase seizure frequency without leading to status epilepticus in PWE. CLZ-associated side effects were found to be tolerable despite the abrupt switch. Future studies may explore the effect of alternative switching ratios.PMID:38382407 | DOI:10.1016/j.yebeh.2024.109690

Source: Epilepsy and Behaviour - February 21, 2024 Category: Neurology Authors: O ğuzhan Fırat Melike Çakan Kutay Demirkan Ne şe Dericioğlu Source Type: research