Genes, Vol. 15, Pages 284: Whole Genome Sequencing and Comparative Genomics of Six Staphylococcus schleiferi and Staphylococcus & nbsp;coagulans Isolates

This study employed a comprehensive approach, utilizing comparative genomics, to identify genomic distinctions between S. schleiferi and S. coagulans, aiming to address the challenges in the accurate classification and diagnosis of these organisms and identify unique features. Whole genome sequencing was performed on six clinical isolates, and their genomes were compared to identify variations in gene content and virulence factors. De novo assembly and annotation revealed two samples as S. coagulans and four samples as S. schleiferi. Analysis of the core genomes revealed conserved regions crucial for defining species identity, while accessory genomic elements contained unique genes, possibly impacting the pathogenicity of the species.
Source: Genes - Category: Genetics & Stem Cells Authors: Tags: Article Source Type: research