OGG1 prevents atherosclerosis-induced vascular endothelial cell injury through mediating DNA damage repair

CONCLUSION: Over-expression of OGG1 improves DNA repair. Briefly, OGG1 over-expression enhances the DNA damage repair of ECs by regulating the expression levels of γH2AX, RAD51 and POLB, thereby enhancing cell viability and reducing apoptosis.PMID:38363604 | DOI:10.3233/CH-232082

Source: Clinical Hemorheology and Microcirculation - February 16, 2024 Category: Hematology Authors: Yi-Ming Zhang Guo-Hua Wang Miao-Jun Xu Gan Jin Source Type: research